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Pre-eclampsia Eclam 內(nèi)容預(yù)覽:
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Pre-eclampsia, Eclampsia and HELLP syndrome
Dr.Victor M De Leon Anzures
Hospital O,horan UCIA
Medicina Critica y Terapia Intensiva
“a disorder associated with pregnancy consisting of hypertension, proteinuria and new-onset dependent oedema, most commonly after 20 weeks of gestation”
Aetiology
Exact pathophysiology unknown
Possible causes-
dysfunction of the uteroplacental bed leading to vasoconstriction, platelet aggregation and hypercoagulability
altered CoV reactivity, vasospasm, microthrombi, implantation problems, hypertension etc
Mortality/Morbidity
Maternal: 8-36% most frequently related to seizure activity
Foetal: 13-30% most frequently related to iatrogenic prematurity
Signs
Hypertension
Tachycardia and tachypnoea
Creps or wheeze on auscultation
Neurological deficit
Hyperreflexia
Petechiae, intracranial haemorrhage
Generalised oedema
Small uterus for dates
Risk Factors
Low socioeconomic class
Multiple foetuses, or hydatid
Maternal age <20 or >35yrs
Primip
Gestational or pre-gestational DM
Renal disease
Afro Caribbean- twice as likely
Family history- four times the risk
當(dāng)過多的子宮出血(包括經(jīng)量過大、經(jīng)期延長或行經(jīng)周期縮短)不是由于可證實的盆...[詳細(xì)]
由于宮腔容積明顯縮小,附著于子宮壁的胎盤不能縮小而與相應(yīng)子宮壁發(fā)生錯位剝離...[詳細(xì)]
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